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Modulation of fronto-parietal and autonomic activity underpins preserved working memory in middle-aged adults

Myriam CAYRE (1), Laure SPIESER (2), Anaïs GUILLE, Nathalie BARIL (2), Arnaud WEILL (3), Caroline CHAMBON (1) 

(1) Réadapt2C Team ; (2) Service d'Expérimentation Humaine ; (3) DI²S²C

Abstract:

Background

Cognitive aging is a heterogeneous process, often diverging from chronological age. However, it remains unclear when early signs of cognitive decline emerge and which neurophysiological markers distinguish age-related cognitive alteration from preserved performances. This study aimed to identify early indicators of cognitive versus chronological aging.

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